This is America’s Moment United to End the Fentanyl Crisis

This War Ends With American Innovation. ARMR is on the Front Lines

More Than A Health Threat

Overdose is taking more young lives than car accidents, cancer, or heart attacks every single year

#1 Killer

Overdose is the leading cause of death for adults aged 18-45 in the United States

#	CRISIS	ESTIMATED U.S. DEATHS	tIME PERIOD
1	Drug Overdose	1,250,000	1999-2024
2	COVID-19	1,200,000	2020-2024
3	HIV/AIDS	700,000	1981-Present
4	1918 Spanish Flu	675,000	1918
5	Civil War (All Causes)	620,000	1861-1865
6	World War II (Combat Deaths)	400,000	1941-1945
7	World War I (Combat Deaths)	116,000	1917-1918
8	Vietnam War (Combat Deaths)	58,000	1965-1975

0

Estimated fatal and nonfatal overdoses since 2000.

0

Cost of the opioid epidemic in the United States as of 2023.

0

Estimated American Overdose Casualties Every Single Day.

Today’s Treatments Can’t Keep Up

The Fentanyl Era Demands More Than Rescue

Current Solutions

Reactive

Reactive, requires someone’s help, only effective after tragedy strikes

Treatment Gap

77%

of people do not feel capable of responding to an opioid overdose

armr’s Solution

Preventative

In development for prevention, addressing the root cause before tragedy strikes

Current Solutions

Reactive

Reactive, requires someone’s help, only effective after tragedy strikes

Treatment Gap

77%

of people do not feel capable of responding to an opioid overdose

Treatment Gap

77%

of people do not feel capable of responding to an opioid overdose

No effect against Xylazine, Nitazenes, etc

Often requires multiple doses

Requires access, awareness & training

Requires someone’s help

Requires fast administration

No lasting protection

armr’s Solution

Preventative

In development for prevention, addressing the root cause before tragedy strikes

How Does Fentanyl Kill? Overdose Starts with the Brain

Fentanyl rapidly enters the bloodstream after ingestion

Disrupting brain signals that control vital lung function

Resulting in an overdose within minutes

How Our Immunotherapy Works

Engineered for Prevention. Designed for Defense.

Arming Americans with Innovative and Improved Treatments

Scaleable, preventative administration (Like a tetanus shot)

Working with the body to produce a protective immune response

The protective response acts as armor against synthetic drug threats

Rendering lethal synthetic drugs such as fentanyl harmless

Resulting in a life saved before tragedy strikes

ARMR technology is already backed by the
Department of Defense through it’s foundational license

Military Funding Initiatives (DoD)

Federal Health Agencies (HHS)

*Logos represent opportunities ARMR has identified

Fighting the Same Fight

ARMR and the United States Against the Overdose Crisis

Fentanyl is Center Stage

Healthcare Alignment

Defense Alignment

Policy Alignment

Executive Alignment

Family Alignment

Healthcare Alignment

Defense Alignment

Policy Alignment

Executive Alignment

Family Alignment

This is a Chance to Solve the Crisis for Millions in Need

Drug Threats are Rapidly Evolving Leaving Americans Defenseless

Current treatments are useless against some emerging threats

ARMR Defense Labs is being built to answer the call

Carfentanil
100x more potent than fentanyl

Xylazine
(NARCAN HAS NO EFFECT)

Nitazenes
Can be more potent than fentanyl

Medetomidine
(NARCAN HAS NO EFFECT)

Future Threats

Rescue Won’t Solve The Overdose Crisis Prevention Has A Chance

ARMR vs. Existing Treatments

Product	aRMR Sciences-100*	Existing Treatments
How is it used?	Preventatively- Like police wearing bullet proof vests	Reactively - Emergency situations when tragedy strikes
Who is this for?	Parents who want protection for their teens Police officer who wants an added layer of protection Opioid use disorder patient	People who are already experiencing overdose
When to take?	Before exposure (targeting 6-12 months of coverage)	After exposure (2-3 minutes after tragedy strikes)
Does it have side effects?	Minor known side effects	Occasional immediate and severe side effects
Is it an injection?	Starting as an injection with nasal spray being researched	Nasal spray